Peptide and compound reference
A reference on peptides, with the evidence graded.
Every entry separates what human trials show from what animal work shows from what people report, and says plainly which is which. Claims carry a named source. Where no source exists, the entry says “no established dosing” rather than inventing a number. Nothing is sold here.
Graded, not guessed
Every entry is marked E1 to E5, or Q, so you can see at a glance whether a claim comes from an approved label, a clinical trial, or a forum post.
Sourced or silent
A dose or a figure prints only when a named source backs it. No source means the entry says so, never a number pulled from nowhere.
Nothing for sale
No products, no vendor links, no affiliate deals. This is a reference, and it stays one.
How entries are graded
Recent entries
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Melanotan 2
Melanotan II was never approved and has never completed a human trial for tanning or libido; it is the unmodified parent compound of two drugs (afamelanotide, bremelanotide) that were each derived from it specifically to remove one of its side effects. Case reports document priapism and concerning changes to existing moles.
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Melanotan 1
Melanotan 1 (afamelanotide) is FDA- and EMA-approved as Scenesse, a 16 mg implant given once every 60 days for erythropoietic protoporphyria, not for tanning. Tanning and libido effects are real but are not what the drug is approved or tested for as a primary outcome.
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PT-141
PT-141 (bremelanotide) is FDA-approved as Vyleesi, an on-demand 1.75 mg subcutaneous injection for hypoactive sexual desire disorder in premenopausal women. It has no approval and no published Phase 3 trial for use in men, despite circulating that way.
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DSIP
DSIP is a 1977-discovered nonapeptide with genuine, though decades-old, blinded and placebo-controlled human trials. Those trials found modest effects on ACTH but no clean, reproduced sleep-architecture effect in a healthy person, which is a different finding than the compound’s name and modern marketing suggest.
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Triptorelin
Triptorelin is an FDA-approved GnRH agonist (Trelstar, Decapeptyl, Triptodur) used to suppress sex hormone production for prostate cancer and central precocious puberty, with decades of Phase 3 evidence. Its approved mechanism is hormone suppression, not optimization, and it has no approved or trial-supported general wellness use.
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Gonadorelin
Gonadorelin is FDA-approved synthetic GnRH, historically used for diagnostic pituitary testing and, via a dedicated pulsatile pump, to induce ovulation. Its now-common off-label use in TRT protocols, injected two to three times weekly, does not reproduce the roughly hourly pulse its mechanism depends on and lacks a dedicated trial.
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Oxytocin
Oxytocin is FDA-approved as an IV/IM obstetric drug (Pitocin) for labor and postpartum bleeding, a completely different use from the unapproved intranasal form studied for social cognition and psychiatric conditions. A 2026 meta-analysis of 42 RCTs found an overall effect close to zero for that intranasal use.
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Kisspeptin-10
Kisspeptin-10 is the short bioactive fragment of an endogenous reproductive hormone. Real human trials exist for this hormone family, including a Phase 2 IVF trigger trial with a 95% oocyte maturation rate, but almost all of the substantial trial work used the longer-acting kisspeptin-54, not kisspeptin-10 specifically.
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Cortexin
Cortexin is a manufactured mixture of polypeptides from young cattle or pig cerebral cortex, a Russian bioregulator drug related in concept to Cerebrolysin. Its human trials are small, Russian-language, and tested it via nasal electrophoresis or combined with breathing exercises, not as a standalone injection against placebo.