Phase 1 Study of CT-996 in Overweight/Obese Participants and Patients With Type 2 Diabetes Mellitus

This is a registry record, not a result. A trial being listed, recruiting or completed says nothing by itself about whether the compound works or is safe.

Registry numberNCT05814107
StatusCompleted
PhasePhase 1
SponsorCarmot Australia First Pty Ltd
Enrollment94 participants
DesignInterventional, Randomized, Sequential, Masking: Double
ConditionsType 2 Diabetes; Overweight or Obesity
InterventionsCT-996; Placebo
StartMay 9, 2023
Primary completionNov 7, 2025
Study completionNov 7, 2025
Results postedNot yet
Registry last updatedNov 28, 2025
CollaboratorsCarmot Therapeutics, Inc.; Hoffmann-La Roche

Compounds on this site that cite this trial

What the registry says the trial is about

This study is designed to assess the safety and tolerability, pharmacokinetics, and pharmacodynamics of CT-996 in overweight/obese participants and participants with Type 2 Diabetes Mellitus (T2DM).

Primary outcomes

These are what the trial was designed to measure first. They are registered in advance, which is what makes a later result checkable.

Outcome measureTime frame
Incidence of Treatment-Emergent Adverse EventsFrom first study drug administration until last safety follow-up (up to 31 days [Part 1] or 58 days [Parts 2 and 3])

12 secondary outcomes also registered. See the registry record for the full list.

Source: ClinicalTrials.gov (U.S. National Library of Medicine). Last checked against the registry on Oct 3, 2026. See the trial changes feed for what has changed recently.