Cosmetic and topical - PeptideBlog

Cosmetic and topical

Research area

Cosmetic and topical

Compounds studied or marketed for topical, cosmetic use -- skin, hair, and related applications.

4 entries in this category.

  • Argireline

    Argireline (acetyl hexapeptide-3/8) is a topical cosmetic peptide developed by Lipotec that is proposed to modestly reduce facial-muscle signaling similar in concept to botulinum toxin. Small industry-affiliated human studies report modest wrinkle-depth improvements; independent industry survey data puts real-world formulation concentrations at roughly 0.005% or less.

  • GHK

    GHK is the plain, copper-free tripeptide glycyl-L-histidyl-L-lysine — distinct from GHK-Cu, the copper complex that carries almost all of the published research and commercial products associated with the "GHK" name.

  • Matrixyl

    Matrixyl (palmitoyl pentapeptide-4, Pal-KTTKS) is a Sederma-developed topical cosmetic peptide proposed to stimulate collagen-related repair signaling in skin. Laboratory data supports the mechanism and a small manufacturer-affiliated human study reported modest photoaging improvement; independent industry survey data puts real-world formulation concentrations at roughly 0.0012% or less.

  • SNAP-8

    SNAP-8 (acetyl octapeptide-3) is a topical cosmetic peptide modeled on SNAP-25, marketed to reduce expression lines. Evidence is almost entirely cosmetic-industry-sponsored, not independent clinical trials.