A Study of Enicepatide (CT-388) in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity

This is a registry record, not a result. A trial being listed, recruiting or completed says nothing by itself about whether the compound works or is safe.

Registry numberNCT06525935
StatusCompleted
PhasePhase 2
SponsorCarmot Therapeutics, Inc.
Enrollment469 participants
DesignInterventional, Randomized, Parallel, Masking: Double
ConditionsObesity; Overweight
InterventionsPlacebo; Enicepatide
StartAug 16, 2024
Primary completionDec 8, 2025
Study completionDec 8, 2025
Results postedNot yet
Registry last updatedApr 17, 2026
CollaboratorsHoffmann-La Roche

Compounds on this site that cite this trial

What the registry says the trial is about

This is a multi-center, randomized, double-blind, placebo-controlled, parallel group dose-finding study to evaluate the efficacy and safety of enicepatide at low, middle, and high doses in participants with obesity or who are overweight with at least one weight-related comorbidity.

Primary outcomes

These are what the trial was designed to measure first. They are registered in advance, which is what makes a later result checkable.

Outcome measureTime frame
Percent Change in Body Weight from Baseline to Week 48Baseline to Week 48

15 secondary outcomes also registered. See the registry record for the full list.

Source: ClinicalTrials.gov (U.S. National Library of Medicine). Last checked against the registry on Oct 3, 2026. See the trial changes feed for what has changed recently.