A Randomized, Double-blind, Placebo-controlled, Five Parallel Groups Efficacy and Safety Study of NS 2330 (Tesofensine) (0.125 mg, 0.25 mg, 0.5 mg and 1.0 mg) Administered Orally Once Daily Over 14 Weeks in Levodopa Treated Parkinson Patients With Motor Fluctuations

This is a registry record, not a result. A trial being listed, recruiting or completed says nothing by itself about whether the compound works or is safe.

Registry numberNCT00148512
StatusCompleted
PhasePhase 2
SponsorBoehringer Ingelheim
Enrollment254 participants
DesignInterventional, Randomized, Parallel, Masking: Double
ConditionsParkinson Disease
Interventions1. Tesofensine (NS 2330)
StartMar 2003
Primary completionFeb 2005
Study completionFeb 2005
Results postedNot yet
Registry last updatedOct 29, 2013

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What the registry says the trial is about

The primary objective of this exploratory study is to investigate the efficacy and safety of tesofensine in daily doses (from 0.125 mg to 1.0 mg) in comparison to placebo, over a 14-week treatment period in levodopa treated Parkinson patients with motor fluctuations.

Source: ClinicalTrials.gov (U.S. National Library of Medicine). Last checked against the registry on Oct 3, 2026. See the trial changes feed for what has changed recently.