Safety and Efficacy of Bimagrumab and Semaglutide in Adults Who Are Overweight or Obese

This is a registry record, not a result. A trial being listed, recruiting or completed says nothing by itself about whether the compound works or is safe.

Registry numberNCT05616013
StatusCompleted
PhasePhase 2
SponsorEli Lilly and Company
Enrollment507 participants
DesignInterventional, Randomized, Factorial, Masking: Double
ConditionsObesity; Obese; Overweight or Obesity
InterventionsBimagrumab; Semaglutide; Placebo
StartNov 16, 2022
Primary completionMay 16, 2024
Study completionJun 14, 2025
Results postedYes, in the registry
Registry last updatedJul 8, 2026
CollaboratorsVersanis Bio, Inc.

Compounds on this site that cite this trial

What the registry says the trial is about

A phase 2 study to assess the efficacy of bimagrumab alone or in addition to semaglutide to assess efficacy and safety in overweight or obese men and women

Primary outcomes

These are what the trial was designed to measure first. They are registered in advance, which is what makes a later result checkable.

Outcome measureTime frame
Change From Baseline in Body Weight at Week 48Baseline, Week 48

41 secondary outcomes also registered. See the registry record for the full list.

Source: ClinicalTrials.gov (U.S. National Library of Medicine). Last checked against the registry on Oct 3, 2026. See the trial changes feed for what has changed recently.