A Study to Investigate Weight Management With Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Adults With Obesity or Overweight

This is a registry record, not a result. A trial being listed, recruiting or completed says nothing by itself about whether the compound works or is safe.

Registry numberNCT06643728
StatusActive not recruiting
PhasePhase 2
SponsorEli Lilly and Company
Enrollment252 participants
DesignInterventional, Randomized, Parallel, Masking: Double
ConditionsObesity; Overweight
InterventionsBimagrumab; Tirzepatide; Bimagrumab Placebo; Tirzepatide Placebo
StartOct 21, 2024
Primary completionJan 16, 2026
Study completionJan 2027
Results postedNot yet
Registry last updatedMay 26, 2026

Compounds on this site that cite this trial

What the registry says the trial is about

The main purpose of this study is to evaluate the efficacy and safety of Bimagrumab and Tirzepatide, alone or in combination, in adults with obesity or overweight, with at least one obesity related comorbidity, without Type 2 Diabetes. The study will last about 70 weeks.

Primary outcomes

These are what the trial was designed to measure first. They are registered in advance, which is what makes a later result checkable.

Outcome measureTime frame
Percent Change from Baseline in Body WeightBaseline, Week 24

10 secondary outcomes also registered. See the registry record for the full list.

Source: ClinicalTrials.gov (U.S. National Library of Medicine). Last checked against the registry on Oct 3, 2026. See the trial changes feed for what has changed recently.