Intratumoral Injections of LL37 for Melanoma

This is a registry record, not a result. A trial being listed, recruiting or completed says nothing by itself about whether the compound works or is safe.

Registry numberNCT02225366
StatusCompleted
PhasePhase 1 / Phase 2
SponsorM.D. Anderson Cancer Center
Enrollment4 participants
DesignInterventional, Na, Single Group, Masking: None
ConditionsMelanoma
InterventionsLL37; Photographs
StartJul 8, 2015
Primary completionNov 24, 2020
Study completionNov 24, 2020
Results postedYes, in the registry
Registry last updatedDec 9, 2021
CollaboratorsNational Cancer Institute (NCI)

Compounds on this site that cite this trial

What the registry says the trial is about

The goal of this clinical research study is to find the appropriate dose of LL37 that can be given to patients with melanoma. Researchers also want to learn if LL37 can stimulate the immune system to help control the disease.

Primary outcomes

These are what the trial was designed to measure first. They are registered in advance, which is what makes a later result checkable.

Outcome measureTime frame
Number of Participants With Optimal Biological Dose (OBD) of LL37 Based Upon Toxicityonce a week, up to 8 weeks duration

1 secondary outcome also registered. See the registry record for the full list.

Source: ClinicalTrials.gov (U.S. National Library of Medicine). Last checked against the registry on Oct 30, 2026. See the trial changes feed for what has changed recently.

More from M.D. Anderson Cancer Center

Research area: Tissue repair and recovery. Every registered trial we follow is in the clinical trial tracker, and the labels used on this page are explained in our evidence standards.