Research Study Investigating How Well NNC0174-0833 Works in People Suffering From Overweight or Obesity.

This is a registry record, not a result. A trial being listed, recruiting or completed says nothing by itself about whether the compound works or is safe.

Registry numberNCT03856047
StatusCompleted
PhasePhase 2
SponsorNovo Nordisk A/S
Enrollment706 participants
DesignInterventional, Randomized, Parallel, Masking: Quadruple
ConditionsOverweight; Obesity
InterventionsNNC0174-0833; Placebo (NNC0174-0833); Liraglutide 3.0 mg; Placebo (Liraglutide 3.0 mg)
StartMar 1, 2019
Primary completionMar 2, 2020
Study completionMar 25, 2021
Results postedYes, in the registry
Registry last updatedJul 5, 2024

Compounds on this site that cite this trial

What the registry says the trial is about

This study will look at the change in body weight in people taking NNC0174-0833, liraglutide and "dummy" medicine, from the start to the end of the study. As well as taking the medicine, participants will have talks with study staff about healthy food choices, how to be more physically active and what participants can do to lose weight. Participants will either take NNC0174-0833, liraglutide or "dummy" medicine - which treatment participants get is decided by chance. Participants will need to take one injection once a week or once a day, depending on the treatment. The study medicine is injected with a thin needle in a skin fold in the stomach, thigh or upper arm. The study will last for about 8 months. Participants will have 12 clinic visits with the study doctor.

Primary outcomes

These are what the trial was designed to measure first. They are registered in advance, which is what makes a later result checkable.

Outcome measureTime frame
Change in Body Weight (%)From baseline (week 0) to week 26

26 secondary outcomes also registered. See the registry record for the full list.

Source: ClinicalTrials.gov (U.S. National Library of Medicine). Last checked against the registry on Oct 3, 2026. See the trial changes feed for what has changed recently.